UM Surabaya Lecturer Explains the Causes of High Uric Acid

• 06 Mar
• 2023

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UM Surabaya Lecturer Explains the Causes of High Uric Acid

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• By Uswah Sahal
• Health
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Gouty arthritis or known as high uric acid in the blood (hyperuresemia) is often a problem for most people who experience it, because the symptoms that arise can interfere with daily activities.

The number of cases of gout (hyperuresemia) in Indonesia reaches 18%, this figure is higher than cases in Thailand, which is as much as 9-11%. This case was most often found at the age of more than 75 years as much as 54.8% but also not a few were found in the age group less than 75 years including young adults as much as 45.2%.

Firman Lecturer at the Faculty of Health Sciences (FIK) UM Surabaya explained, uric acid is the result of the metabolism of purine substances contained in the food that humans consume.

"Actually, uric acid levels in the blood are not always dangerous for the body, if they are maintained within normal limits, that is, for women it is 2.6-6 mg/dl, while for men it is 3.5-7 mg/dl," said Firman Monday (6/6). 3/23)

One of the benefits of uric acid is as an antioxidant, which can break down free radicals in the body. But on the contrary, if high uric acid is more than 7 mg/dl, it can cause several problems in the body, which can be known as signs and symptoms such as sudden joint pain, difficulty walking due to severe joint pain, especially at night, swelling, redness. , a feeling of heat, scaly skin on the joints and feels itchy.

Firman explained that increased uric acid in the blood could be caused by two things. First, too much consumption of foods high in purines, such as nuts and chicken offal. The second is decreased excretion of uric acid levels due to impaired kidney function. These two conditions are the cause of high uric acid (hyperuresemia).

"For this reason, prevention can be done, such as controlling uric acid levels by maintaining a healthy diet, doing regular and regular exercise 3-5 times a week, and maintaining kidney health so that they can always function properly," Firman added.

While treatment based on Clinical Pathway can be done as follows; on the first day the complaint is felt, colchicine 0.5 mg can be given, diclofenat 25-50 mg is given 2-3 times a day. In cases with complaints the first week can be given the drug allupurinol 100-300 mg a day and colchicine 0.5 mg.

“Meanwhile, in cases that occur at 1-3 months, given the drug colchicine 0.5 mg, allupurinol 100-300 mg and diclofenat 25-50 mg. In cases of more than 3 months, given the drug colchicine 0.5 mg, allupurinol 100-300 mg, the dose can be increased to 800 mg and diclofenat 25-50 mg," said Firman.